Defective gut function in drop-dead mutant Drosophila
نویسندگان
چکیده
منابع مشابه
Defective gut function in drop-dead mutant Drosophila.
Mutation of the gene drop-dead (drd) causes adult Drosophila to die within 2 weeks of eclosion and is associated with reduced rates of defecation and increased volumes of crop contents. In the current study, we demonstrate that flies carrying the strong allele drd(lwf) display a reduction in the transfer of ingested food from the crop to the midgut, as measured both as a change in the steady-st...
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Mutations in the gene drop-dead (drd) cause diverse phenotypes in adult Drosophila melanogaster including early lethality, neurodegeneration, tracheal defects, gut dysfunction, reduced body mass, and female sterility. Despite the identification of the drd gene itself, the causes of early lethality and neurodegeneration in the mutant flies remain unknown. To determine the pattern of drd expressi...
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Mutations of the drop-dead gene in Drosophila melanogaster lead to striking early death of the adult animal. At different times, after emergence from the pupa, individual flies begin to stagger and, shortly thereafter, die. Anatomical examination reveals gross neuropathological lesions in the brain. The life span of flies mutant for the drop-dead gene is four to five times shorter than for norm...
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ژورنال
عنوان ژورنال: Journal of Insect Physiology
سال: 2009
ISSN: 0022-1910
DOI: 10.1016/j.jinsphys.2009.05.011